A novel methylated analogue of L-Mimosine exerts its therapeutic potency through ROS production and ceramide-induced apoptosis in malignant melanoma

Melanoma is an aggressive and highly metastatic type of skin cancer where the design of new therapies is of utmost importance for the clinical management of the disease. Thus, we have aimed to investigate the mode of action by which a novel methylated analogue of L-Mimosine (e.g., L-SK-4) exerts its...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Invest New Drugs
Autori principali: Kyriakou, Sotiris, Cheung, William, Mantso, Theodora, Mitsiogianni, Melina, Anestopoulos, Ioannis, Veuger, Stephany, Trafalis, Dimitris T., Franco, Rodrigo, Pappa, Aglaia, Tetard, David, Panayiotidis, Mihalis I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2021
Soggetti:
Preclinical Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280034/
https://ncbi.nlm.nih.gov/pubmed/33624234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-021-01087-5
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi