Sensitive Detection of Single-Nucleotide Polymorphisms by Solid Nanopores Integrated With DNA Probed Nanoparticles

Single-nucleotide polymorphisms (SNPs) are the abundant forms of genetic variations, which are closely associated with serious genetic and inherited diseases, even cancers. Here, a novel SNP detection assay has been developed for single-nucleotide discrimination by nanopore sensing platform with DNA...

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Bibliographic Details
Published in:Front Bioeng Biotechnol
Main Authors: Wu, Ling Zhi, Ye, Yuan, Wang, Zhi Xuan, Ma, Die, Li, Li, Xi, Guo Hao, Bao, Bi Qing, Weng, Li Xing
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Bioengineering and Biotechnology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279778/
https://ncbi.nlm.nih.gov/pubmed/34277589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.690747
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