Heparin impairs skeletal muscle glucose uptake by inhibiting insulin binding to insulin receptor

AIM: Heparin, a widely used antithrombotic drug has many other anticoagulant‐independent physiological functions. Here, we elucidate a novel role of heparin in glucose homeostasis, suggesting an approach for developing heparin‐targeted therapies for diabetes. METHODS: For serum heparin levels and co...

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Detalhes bibliográficos
Publicado no:Endocrinol Diabetes Metab
Main Authors: Zhu, Canjun, Xu, Zhiyue, Yuan, Yexian, Wang, Tao, Xu, Chang, Yin, Cong, Xie, Peipei, Xu, Pingwen, Ye, Hui, Patel, Nirali, Schaul, Sarah, Wang, Lina, Zhu, Xiaotong, Wang, Songbo, Gao, Ping, Xi, Qianyun, Zhang, Yongliang, Shu, Gang, Jiang, Qingyan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279624/
https://ncbi.nlm.nih.gov/pubmed/34277977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/edm2.253
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