Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines

A series of 11 new substituted 1,5-dihydro-4,1-benzoxazepine derivatives was synthesised to study the influence of the methyl group in the 1-(benzenesulphonyl) moiety, the replacement of the purine by the benzotriazole bioisosteric analogue, and the introduction of a bulky substituent at position 6...

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Bibliografiske detaljer
Udgivet i:J Enzyme Inhib Med Chem
Main Authors: Cruz-López, Olga, Ner, Matilde, Nerín-Fonz, Francho, Jiménez-Martínez, Yaiza, Araripe, David, Marchal, Juan A., Boulaiz, Houria, Gutiérrez-de-Terán, Hugo, Campos, Joaquín M., Conejo-García, Ana
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2021
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279156/
https://ncbi.nlm.nih.gov/pubmed/34251942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1948841
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