Enhancement of Tumor Cell Death by Combining gef Gene Mediated Therapy and New 1,4-Benzoxazepin-2,6-Dichloropurine Derivatives in Breast Cancer Cells

New treatment modalities are urgently needed to better manage advanced breast cancer. Combination therapies are usually more effective than monotherapy. In this context, the use of cyclic and acyclic O,N-acetals derivative compounds in combination with the suicide gef gene shown a potent anti-tumor...

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Publicat a:Front Pharmacol
Autors principals: Ramírez, Alberto, Conejo-García, Ana, Griñán-Lisón, Carmen, López-Cara, Luisa C., Jiménez, Gema, Campos, Joaquín M., Marchal, Juan A., Boulaiz, Houria
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070671/
https://ncbi.nlm.nih.gov/pubmed/30093861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00798
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