Intra-Ommaya Compartmental Radioimmunotherapy using (131)I-Omburtamab— Pharmacokinetic Modeling to Optimize Therapeutic Index

PURPOSE: Radioimmunotherapy (RIT) delivered through the cerebrospinal fluid (CSF) has been shown to be a safe and promising treatment for leptomeningeal metastases. Pharmacokinetic models for intra-Ommaya anti-GD2 monoclonal antibody (131)I-3F8 have been proposed to improve therapeutic effect while...

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書誌詳細
出版年:Eur J Nucl Med Mol Imaging
主要な著者: Yerrabelli, Rahul S., He, Ping, Fung, Edward K., Kramer, Kim, Zanzonico, Pat B., Humm, John L., Guo, Hongfen, Pandit-Taskar, Neeta, Larson, Steven M., Cheung, Nai-Kong V.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279045/
https://ncbi.nlm.nih.gov/pubmed/33047248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-020-05050-z
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