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Intra-Ommaya Compartmental Radioimmunotherapy using (131)I-Omburtamab— Pharmacokinetic Modeling to Optimize Therapeutic Index
PURPOSE: Radioimmunotherapy (RIT) delivered through the cerebrospinal fluid (CSF) has been shown to be a safe and promising treatment for leptomeningeal metastases. Pharmacokinetic models for intra-Ommaya anti-GD2 monoclonal antibody (131)I-3F8 have been proposed to improve therapeutic effect while...
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| Publicado no: | Eur J Nucl Med Mol Imaging |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8279045/ https://ncbi.nlm.nih.gov/pubmed/33047248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-020-05050-z |
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