Cellular hallmarks of aging emerge in the ovary prior to primordial follicle depletion

Decline in ovarian reserve with advancing age is associated with reduced fertility and the emergence of metabolic disturbances, osteoporosis, and neurodegeneration. Recent studies have provided insight into connections between ovarian insufficiency and systemic aging, although the basic mechanisms t...

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Publicat a:Mech Ageing Dev
Autors principals: Ansere, Victor A., Ali-Mondal, Samim, Sathiaseelan, Roshini, Garcia, Driele N., Isola, José V. V., Henseb, Jéssica D., Saccon, Tatiana D., Ocañas, Sarah R., Tooley, Kyla B., Stout, Michael B., Schneider, Augusto, Freeman, Willard M.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279026/
https://ncbi.nlm.nih.gov/pubmed/33383072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2020.111425
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