Cellular hallmarks of aging emerge in the ovary prior to primordial follicle depletion

Decline in ovarian reserve with advancing age is associated with reduced fertility and the emergence of metabolic disturbances, osteoporosis, and neurodegeneration. Recent studies have provided insight into connections between ovarian insufficiency and systemic aging, although the basic mechanisms t...

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Veröffentlicht in:Mech Ageing Dev
Hauptverfasser: Ansere, Victor A., Ali-Mondal, Samim, Sathiaseelan, Roshini, Garcia, Driele N., Isola, José V. V., Henseb, Jéssica D., Saccon, Tatiana D., Ocañas, Sarah R., Tooley, Kyla B., Stout, Michael B., Schneider, Augusto, Freeman, Willard M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279026/
https://ncbi.nlm.nih.gov/pubmed/33383072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2020.111425
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