Serum Amyloid A1 Induces Classically Activated Macrophages: A Role for Enhanced Fibril Formation

AA amyloidosis belongs to the group of amyloid diseases which can follow chronic inflammatory conditions of various origin. The disease is characterized by the deposition of insoluble amyloid fibrils formed by serum amyloid A1 (SAA1) leading eventually to organ failure. Macrophages are intimately in...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gaiser, Ann-Kathrin, Bauer, Shanna, Ruez, Stephanie, Holzmann, Karlheinz, Fändrich, Marcus, Syrovets, Tatiana, Simmet, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278318/
https://ncbi.nlm.nih.gov/pubmed/34276683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.691155
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