MTHFD2 promotes tumorigenesis and metastasis in lung adenocarcinoma by regulating AKT/GSK‐3β/β‐catenin signalling

Recent studies have demonstrated that one‐carbon metabolism plays a significant role in cancer development. Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), a mitochondrial enzyme of one‐carbon metabolism, has been reported to be dysregulated in many cancers. However, the specific role and mechan...

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Pubblicato in:J Cell Mol Med
Autori principali: Shi, Yangfeng, Xu, Yiming, Yao, Jianchang, Yan, Chao, Su, Hua, Zhang, Xue, Chen, Enguo, Ying, Kejing
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278097/
https://ncbi.nlm.nih.gov/pubmed/34121323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16715
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