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Amine derivatives of furocoumarin induce melanogenesis by activating Akt/GSK-3β/β-catenin signal pathway

BACKGROUND: Melanogenesis, or the biosynthesis of melanin, plays a critical role in the pigmentation of skin, hair, and eyes. Reduced melanogenesis may lead to depigmentation conditions such as vitiligo. Psoralen, a furocoumarin derivative, is closely associated with melanogenesis, and its derivativ...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zang, Deng, Niu, Chao, Aisa, Haji Akber
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387609/
https://ncbi.nlm.nih.gov/pubmed/30858693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S180960
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