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SENP1 modulates microglia‐mediated neuroinflammation toward intermittent hypoxia‐induced cognitive decline through the de‐SUMOylation of NEMO

Intermittent hypoxia (IH)‐induced cognition decline is related to the neuroinflammation in microglia. SUMOylation is associated with multiple human diseases, which can be reversed by sentrin/SUMO‐specific proteases 1 (SENP1). Herein, we investigated the role of SENP1 in IH‐induced inflammation and c...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Wang, Hongwei, Yang, Tianyun, Sun, Jinyuan, Zhang, Sisen, Liu, Song
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278079/
https://ncbi.nlm.nih.gov/pubmed/34120412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16689
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