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SENP1 modulates microglia‐mediated neuroinflammation toward intermittent hypoxia‐induced cognitive decline through the de‐SUMOylation of NEMO

Intermittent hypoxia (IH)‐induced cognition decline is related to the neuroinflammation in microglia. SUMOylation is associated with multiple human diseases, which can be reversed by sentrin/SUMO‐specific proteases 1 (SENP1). Herein, we investigated the role of SENP1 in IH‐induced inflammation and c...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Wang, Hongwei, Yang, Tianyun, Sun, Jinyuan, Zhang, Sisen, Liu, Song
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278079/
https://ncbi.nlm.nih.gov/pubmed/34120412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16689
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