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The P300/XBP1s/Herpud1 axis promotes macrophage M2 polarization and the development of choroidal neovascularization

Neovascular age‐related macular degeneration (AMD), which is characterized by choroidal neovascularization (CNV), leads to vision loss. M2 macrophages produce vascular endothelial growth factor (VEGF), which aggravates CNV formation. The histone acetyltransferase p300 enhances the stability of splic...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Li, Wendie, Wang, Ying, Zhu, Linling, Du, Shu, Mao, Jinghai, Wang, Yanyan, Wang, Sangsang, Bo, Qingyun, Tu, Yuanyuan, Yi, QuanYong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278076/
https://ncbi.nlm.nih.gov/pubmed/34057287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16673
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