Genomic Heterogeneity and Copy Number Variant Burden are Associated with Poor Recurrence Free Survival and 11q Loss in HPV+ Squamous Cell Carcinoma of the Oropharynx

BACKGROUND: HPV positive squamous cell carcinoma of the oropharynx (OPSCC) is the most prevalent HPV associated malignancy in the United States. Favorable treatment outcomes have led to increasing interest in treatment de-escalation to reduce treatment morbidity; as well as developing prognostic mar...

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Dades bibliogràfiques
Publicat a:Cancer
Autors principals: Schrank, Travis P., Lenze, Nicholas, Landess, Lee P., Hoyle, Alan, Parker, Joel, Lal, Asim, Sheth, Siddharth, Chera, Bhishamjit S., Patel, Samip N., Hackman, Trevor G., Major, M. Ben, Issaeva, Natalia, Yarbrough, Wendell G.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8277690/
https://ncbi.nlm.nih.gov/pubmed/33819343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.33504
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