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Synthesis and characterization of [(18)F]JNJ-46356479 as the first (18)F-labeled PET imaging ligand for metabotropic glutamate receptor 2
PURPOSE: Metabotropic glutamate receptor 2 (mGluR2) has been implicated in various psychiatric and neurological disorders, such as schizophrenia and Alzheimer’s disease. We have previously developed [(11)C]7 as a PET radioligand for imaging mGluR2. Herein, [(18)F]JNJ-46356479 ([(18)F]8) was synthesi...
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| Publicado no: | Mol Imaging Biol |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8277681/ https://ncbi.nlm.nih.gov/pubmed/33559035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-021-01586-0 |
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