Selective targeting of peripheral cannabinoid receptors prevents behavioral symptoms and sensitization of trigeminal neurons in mouse models of migraine and medication overuse headache.

Migraine affects ~15% of the world’s population greatly diminishing their quality of life. Current preventative treatments are effective in only a subset of migraine patients, and while cannabinoids appear beneficial in alleviating migraine symptoms, central nervous system (CNS) side effects limit t...

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Bibliografiske detaljer
Udgivet i:	Pain
Main Authors:	Yamamoto, Toru, Mulpuri, Yatendra, Izraylev, Mikhail, Li, Qianyi, Simonian, Menooa, Kramme, Christian, Schmidt, Brian L., Seltzman, Herbert H., Spigelman, Igor
Format:	Artigo
Sprog:	Inglês
Udgivet:	2021
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC8277668/ https://ncbi.nlm.nih.gov/pubmed/33534356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000002214
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Selective targeting of peripheral cannabinoid receptors prevents behavioral symptoms and sensitization of trigeminal neurons in mouse models of migraine and medication overuse headache.

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