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Machine Learning Uses Chemo-Transcriptomic Profiles to Stratify Antimalarial Compounds With Similar Mode of Action

The rapid development of antimalarial resistance motivates the continued search for novel compounds with a mode of action (MoA) different to current antimalarials. Phenotypic screening has delivered thousands of promising hit compounds without prior knowledge of the compounds’ exact target or MoA. W...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: van Heerden, Ashleigh, van Wyk, Roelof, Birkholtz, Lyn-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8277430/
https://ncbi.nlm.nih.gov/pubmed/34268139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.688256
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