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Using Machine Learning to Predict Synergistic Antimalarial Compound Combinations With Novel Structures

The parasite Plasmodium falciparum is the most lethal species of Plasmodium to cause serious malaria infection in humans, and with resistance developing rapidly novel treatment modalities are currently being sought, one of which being combinations of existing compounds. The discovery of combinations...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Mason, Daniel J., Eastman, Richard T., Lewis, Richard P. I., Stott, Ian P., Guha, Rajarshi, Bender, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176478/
https://ncbi.nlm.nih.gov/pubmed/30333748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01096
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