Ovarian Hyperandrogenism and Response to Gonadotropin-releasing Hormone Analogues in Primary Severe Insulin Resistance

CONTEXT: Insulin resistance (IR) is associated with polycystic ovaries and hyperandrogenism, but underpinning mechanisms are poorly understood and therapeutic options are limited. OBJECTIVE: To characterize hyperandrogenemia and ovarian pathology in primary severe IR (SIR), using IR of defined molec...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Huang-Doran, Isabel, Kinzer, Alexandra B, Jimenez-Linan, Mercedes, Thackray, Kerrie, Harris, Julie, Adams, Claire L, de Kerdanet, Marc, Stears, Anna, O’Rahilly, Stephen, Savage, David B, Gorden, Phillip, Brown, Rebecca J, Semple, Robert K
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8277216/
https://ncbi.nlm.nih.gov/pubmed/33901270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgab275
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