Insulin Resistance Is a Sufficient Basis for Hyperandrogenism in Lipodystrophic Women with Polycystic Ovarian Syndrome

CONTEXT: The lipodystrophies (LD) are characterized by metabolic abnormalities (insulin resistance, hypertriglyceridemia, and diabetes) and a polycystic ovarian syndrome (PCOS) phenotype. Therapeutic administration of leptin improves insulin sensitivity and the metabolic features. OBJECTIVE: The obj...

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Autori principali: Lungu, Andreea O., Safar Zadeh, Elika, Goodling, Anne, Cochran, Elaine, Gorden, Phillip
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2012
Soggetti:
Endocrine Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275358/
https://ncbi.nlm.nih.gov/pubmed/22090274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-1896
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