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A BAYESIAN NONPARAMETRIC MODEL FOR INFERRING SUBCLONAL POPULATIONS FROM STRUCTURED DNA SEQUENCING DATA

There are distinguishing features or “hallmarks” of cancer that are found across tumors, individuals, and types of cancer, and these hallmarks can be driven by specific genetic mutations. Yet, within a single tumor there is often extensive genetic heterogeneity as evidenced by single-cell and bulk D...

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Detalhes bibliográficos
Publicado no:Ann Appl Stat
Main Authors: He, Shai, Schein, Aaron, Sarsani, Vishal, Flaherty, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8277113/
https://ncbi.nlm.nih.gov/pubmed/34262633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/20-aoas1434
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