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SCSIM: Jointly simulating correlated single-cell and bulk next-generation DNA sequencing data

BACKGROUND: Recently, it has become possible to collect next-generation DNA sequencing data sets that are composed of multiple samples from multiple biological units where each of these samples may be from a single cell or bulk tissue. Yet, there does not yet exist a tool for simulating DNA sequenci...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Giguere, Collin, Dubey, Harsh Vardhan, Sarsani, Vishal Kumar, Saddiki, Hachem, He, Shai, Flaherty, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249349/
https://ncbi.nlm.nih.gov/pubmed/32456609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03550-1
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