TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity

To control viral infection, vertebrates rely on both inducible interferon responses and less well characterized cell intrinsic responses comprised of “at the ready” antiviral effector proteins. Here, we show that E3 ubiquitin ligase TRIM7 is a cell intrinsic antiviral effector that restricts multipl...

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Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Fan, Wenchun, Mar, Katrina B., Sari, Levent, Gaszek, Ilona K., Cheng, Qiang, Evers, Bret M., Shelton, John M., Wight-Carter, Mary, Siegwart, Daniel J., Lin, Milo M., Schoggins, John W.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8276836/
https://ncbi.nlm.nih.gov/pubmed/34062120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.04.047
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