PD-1(+)CXCR5(−)CD4(+) Th-CXCL13 cell subset drives B cells into tertiary lymphoid structures of nasopharyngeal carcinoma

BACKGROUND: A major current challenge is to exploit tertiary lymphoid structures (TLSs) to promote the lymphocyte infiltration, activation and differentiation by tumor antigens to increase antitumor immune responses. The mechanisms that underlie the role of TLS formation in the adaptive immune respo...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Li, Jiang-Ping, Wu, Chang-You, Chen, Ming-Yuan, Liu, Shang-Xin, Yan, Shu-Mei, Kang, Yin-Feng, Sun, Cong, Grandis, Jennifer R, Zeng, Mu-Sheng, Zhong, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Basic Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8276302/
https://ncbi.nlm.nih.gov/pubmed/34253636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-002101
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