Loss of Deacetylation Enzymes Hdac6 and Sirt2 Promotes Acetylation of Cytoplasmic Tubulin, but Suppresses Axonemal Acetylation in Zebrafish Cilia

Cilia are evolutionarily highly conserved organelles with important functions in many organs. The extracellular component of the cilium protruding from the plasma membrane comprises an axoneme composed of microtubule doublets, arranged in a 9 + 0 conformation in primary cilia or 9 + 2 in motile cili...

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Publicado en:Front Cell Dev Biol
Autores principales: Łysyganicz, Paweł K., Pooranachandran, Niedharsan, Liu, Xinming, Adamson, Kathryn I., Zielonka, Katarzyna, Elworthy, Stone, van Eeden, Fredericus J., Grierson, Andrew J., Malicki, Jarema J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8276265/
https://ncbi.nlm.nih.gov/pubmed/34268305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.676214
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