Mesenchymal stromal cells expressing a dominant‐negative high mobility group A1 transgene exhibit improved function during sepsis

High mobility group (HMG)A proteins are nonhistone chromatin proteins that bind to the minor groove of DNA, interact with transcriptional machinery, and facilitate DNA‐directed nuclear processes. HMGA1 has been shown to regulate genes involved with systemic inflammatory processes. We hypothesized th...

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Bibliografiske detaljer
Udgivet i:J Leukoc Biol
Main Authors: Kwon, Min‐Young, Ghanta, Sailaja, Ng, Julie, Castano, Ana P., Han, Junwen, Ith, Bonna, Lederer, James A., El‐Chemaly, Souheil, Chung, Su Wol, Liu, Xiaoli, Perrella, Mark A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Host Defense and Pathophysiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8275698/
https://ncbi.nlm.nih.gov/pubmed/33438259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4A0720-424R
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