Mesenchymal stromal cells expressing a dominant‐negative high mobility group A1 transgene exhibit improved function during sepsis

High mobility group (HMG)A proteins are nonhistone chromatin proteins that bind to the minor groove of DNA, interact with transcriptional machinery, and facilitate DNA‐directed nuclear processes. HMGA1 has been shown to regulate genes involved with systemic inflammatory processes. We hypothesized th...

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Vydáno v:J Leukoc Biol
Hlavní autoři: Kwon, Min‐Young, Ghanta, Sailaja, Ng, Julie, Castano, Ana P., Han, Junwen, Ith, Bonna, Lederer, James A., El‐Chemaly, Souheil, Chung, Su Wol, Liu, Xiaoli, Perrella, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
Host Defense and Pathophysiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8275698/
https://ncbi.nlm.nih.gov/pubmed/33438259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4A0720-424R
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