Disabling the Nuclear Translocalization of RelA/NF-κB by a Small Molecule Inhibits Triple-Negative Breast Cancer Growth

INTRODUCTION: Constitutive activation of NF-κB has been implicated as being contributive to cancer cell growth, drug resistance, and tumor recurrence in many cancers including breast cancer. Activation of NF-κB leads to nuclear translocation of RelA, a critical component of the NF-κB transcription f...

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Enregistré dans:
Détails bibliographiques
Publié dans:Breast Cancer (Dove Med Press)
Auteurs principaux: Kanzaki, Hirotaka, Chatterjee, Avradip, Hossein Nejad Ariani, Hanieh, Zhang, Xinfeng, Chung, Stacey, Deng, Nan, Ramanujan, V Krishnan, Cui, Xiaojiang, Greene, Mark I, Murali, Ramachandran
Format: Artigo
Langue:Inglês
Publié: Dove 2021
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8275049/
https://ncbi.nlm.nih.gov/pubmed/34262338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S310231
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