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A simple method of hiPSCs differentiation into insulin-producing cells is improved with vitamin C and RepSox

Human induced pluripotent stem cells (hiPSCs) are considered a promising source of pancreatic β-cells for the treatment of diabetes. However, this approach is limited by issues such as low efficiency and high cost. Here, we have developed a new protocol to induce insulin-producing cells. To reduce c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Horikawa, Ayumi, Mizuno, Keiko, Tsuda, Kyoko, Yamamoto, Takayoshi, Michiue, Tatsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274930/
https://ncbi.nlm.nih.gov/pubmed/34252142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0254373
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