Endothelial arginase 2 mediates retinal ischemia/reperfusion injury by inducing mitochondrial dysfunction

OBJECTIVE: Retinal ischemic disease is a major cause of vision loss. Current treatment options are limited to late-stage diseases, and the molecular mechanisms of the initial insult are not fully understood. We have previously shown that the deletion of the mitochondrial arginase isoform, arginase 2...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Metab
Auteurs principaux: Shosha, Esraa, Fouda, Abdelrahman Y., Lemtalsi, Tahira, Haigh, Stephen, Fulton, David, Ibrahim, Ahmed, Al-Shabrawey, Mohamed, Caldwell, R. William, Caldwell, Ruth B.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2021
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274341/
https://ncbi.nlm.nih.gov/pubmed/34139341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101273
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