Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses

The lack of effective therapies to limit neurovascular injury in ischemic retinopathy is a major clinical problem. This study aimed to examine the role of ureohydrolase enzyme, arginase 1 (A1), in retinal ischemia-reperfusion (IR) injury. A1 competes with nitric oxide synthase (NOS) for their common...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Fouda, Abdelrahman Y., Xu, Zhimin, Shosha, Esraa, Lemtalsi, Tahira, Chen, Jijun, Toque, Haroldo A., Tritz, Rebekah, Cui, Xuezhi, Stansfield, Brian K., Huo, Yuqing, Rodriguez, Paulo C., Smith, Sylvia B., Caldwell, R. William, Narayanan, S. Priya, Caldwell, Ruth B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156564/
https://ncbi.nlm.nih.gov/pubmed/30254218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1051-6
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