Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses

The lack of effective therapies to limit neurovascular injury in ischemic retinopathy is a major clinical problem. This study aimed to examine the role of ureohydrolase enzyme, arginase 1 (A1), in retinal ischemia-reperfusion (IR) injury. A1 competes with nitric oxide synthase (NOS) for their common...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Fouda, Abdelrahman Y., Xu, Zhimin, Shosha, Esraa, Lemtalsi, Tahira, Chen, Jijun, Toque, Haroldo A., Tritz, Rebekah, Cui, Xuezhi, Stansfield, Brian K., Huo, Yuqing, Rodriguez, Paulo C., Smith, Sylvia B., Caldwell, R. William, Narayanan, S. Priya, Caldwell, Ruth B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156564/
https://ncbi.nlm.nih.gov/pubmed/30254218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1051-6
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