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Resveratrol protects intestinal epithelial cells against radiation-induced damage by promoting autophagy and inhibiting apoptosis through SIRT1 activation

Intrinsic autophagy is important for the maintenance of intestinal homeostasis and intestinal regeneration. Ionizing radiation suppresses intrinsic autophagy and reduces damage-induced regeneration in the intestine, resulting in intestinal injury. Resveratrol, a sirtuin 1 (SIRT1) agonist, promotes a...

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Bibliografische gegevens
Gepubliceerd in:J Radiat Res
Hoofdauteurs: Qin, Haoren, Zhang, Heng, Zhang, Xipeng, Zhang, Shiwu, Zhu, Siwei, Wang, Hui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8273810/
https://ncbi.nlm.nih.gov/pubmed/33912959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrab035
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