Resveratrol protects intestinal epithelial cells against radiation-induced damage by promoting autophagy and inhibiting apoptosis through SIRT1 activation

Intrinsic autophagy is important for the maintenance of intestinal homeostasis and intestinal regeneration. Ionizing radiation suppresses intrinsic autophagy and reduces damage-induced regeneration in the intestine, resulting in intestinal injury. Resveratrol, a sirtuin 1 (SIRT1) agonist, promotes a...

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Detalles Bibliográficos
Publicado en:J Radiat Res
Main Authors: Qin, Haoren, Zhang, Heng, Zhang, Xipeng, Zhang, Shiwu, Zhu, Siwei, Wang, Hui
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2021
Assuntos:
Fundamental Radiation Science
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8273810/
https://ncbi.nlm.nih.gov/pubmed/33912959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrab035
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