Factor VIII-Fc Activates Natural Killer Cells via Fc-Mediated Interactions With CD16

The most challenging complication associated with Factor VIII (FVIII) replacement therapy is the development of neutralizing anti-drug antibodies, or inhibitors, which occur in 23-35% of severe (FVIII level <1%) hemophilia A (HA) patients and are a serious hindrance to effective management of HA....

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Udgivet i:Front Immunol
Main Authors: Lagassé, H.A. Daniel, Hopkins, Louis B., Jankowski, Wojciech, Jacquemin, Marc G., Sauna, Zuben E., Golding, Basil
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8273617/
https://ncbi.nlm.nih.gov/pubmed/34262568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.692157
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