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Mutational Landscape of Pirin and Elucidation of the Impact of Most Detrimental Missense Variants That Accelerate the Breast Cancer Pathways: A Computational Modelling Study

Pirin (PIR) protein is highly conserved in both prokaryotic and eukaryotic organisms. Recently, it has been identified that PIR positively regulates breast cancer cell proliferation, xenograft tumor formation, and metastasis, through an enforced transition of G1/S phase of the cell cycle by upregula...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Front Mol Biosci
Κύριοι συγγραφείς: Suleman, Muhammad, Tahir ul Qamar, Muhammad, Saleem, Shoaib, Ahmad, Sajjad, Ali, Syed Shujait, Khan, Haji, Akbar, Fazal, Khan, Wajid, Alblihy, Adel, Alrumaihi, Faris, Waseem, Muhammad, Allemailem, Khaled S.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Frontiers Media S.A. 2021
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8273169/
https://ncbi.nlm.nih.gov/pubmed/34262943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.692835
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