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DNA methylation analysis reveals epimutation hotspots in patients with dilated cardiomyopathy-associated laminopathies

BACKGROUND: Mutations in LMNA, encoding lamin A/C, lead to a variety of diseases known as laminopathies including dilated cardiomyopathy (DCM) and skeletal abnormalities. Though previous studies have investigated the dysregulation of gene expression in cells from patients with DCM, the role of epige...

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Detaylı Bibliyografya
Yayımlandı:Clin Epigenetics
Asıl Yazarlar: Morival, Julien L. P., Widyastuti, Halida P., Nguyen, Cecilia H. H., Zaragoza, Michael V., Downing, Timothy L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8272901/
https://ncbi.nlm.nih.gov/pubmed/34246298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01127-0
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