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DNA methylation analysis reveals epimutation hotspots in patients with dilated cardiomyopathy-associated laminopathies

BACKGROUND: Mutations in LMNA, encoding lamin A/C, lead to a variety of diseases known as laminopathies including dilated cardiomyopathy (DCM) and skeletal abnormalities. Though previous studies have investigated the dysregulation of gene expression in cells from patients with DCM, the role of epige...

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書誌詳細
出版年:Clin Epigenetics
主要な著者: Morival, Julien L. P., Widyastuti, Halida P., Nguyen, Cecilia H. H., Zaragoza, Michael V., Downing, Timothy L.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8272901/
https://ncbi.nlm.nih.gov/pubmed/34246298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01127-0
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