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Immunoproteasome and Non-Covalent Inhibition: Exploration by Advanced Molecular Dynamics and Docking Methods
The selective inhibition of immunoproteasome is a valuable strategy to treat autoimmune, inflammatory diseases, and hematologic malignancies. Recently, a new series of amide derivatives as non-covalent inhibitors of the β1i subunit with K(i) values in the low/submicromolar ranges have been identifie...
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| Pubblicato in: | Molecules |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8271555/ https://ncbi.nlm.nih.gov/pubmed/34279386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26134046 |
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