Levosimendan increases brain tissue oxygen levels after cardiopulmonary resuscitation independent of cardiac function and cerebral perfusion

Prompt reperfusion is important to rescue ischemic tissue; however, the process itself presents a key pathomechanism that contributes to a poor outcome following cardiac arrest. Experimental data have suggested the use of levosimendan to limit ischemia–reperfusion injury by improving cerebral microc...

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Veröffentlicht in:Sci Rep
Hauptverfasser: García-Bardon, Andreas, Kamuf, Jens, Ziebart, Alexander, Liu, Tanghua, Krebs, Nadia, Dünges, Bastian, Kelm, Robert F., Morsbach, Svenja, Mohr, Kristin, Heimann, Axel, Hartmann, Erik K., Thal, Serge C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270955/
https://ncbi.nlm.nih.gov/pubmed/34244561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93621-x
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