Inhalation therapy with the synthetic TIP-like peptide AP318 attenuates pulmonary inflammation in a porcine sepsis model

BACKGROUND: The lectin-like domain of TNF-α can be mimicked by synthetic TIP peptides and represents an innovative pharmacologic option to treat edematous respiratory failure. TIP inhalation was shown to reduce pulmonary edema and improve gas exchange. In addition to its edema resolution effect, TIP...

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Publicado en:BMC Pulm Med
Main Authors: Hartmann, Erik K, Ziebart, Alexander, Thomas, Rainer, Liu, Tanghua, Schad, Arno, Tews, Martha, Moosmann, Bernd, Kamuf, Jens, Duenges, Bastian, Thal, Serge C, David, Matthias
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346123/
https://ncbi.nlm.nih.gov/pubmed/25879802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-015-0002-6
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