Inhalation therapy with the synthetic TIP-like peptide AP318 attenuates pulmonary inflammation in a porcine sepsis model

BACKGROUND: The lectin-like domain of TNF-α can be mimicked by synthetic TIP peptides and represents an innovative pharmacologic option to treat edematous respiratory failure. TIP inhalation was shown to reduce pulmonary edema and improve gas exchange. In addition to its edema resolution effect, TIP...

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Veröffentlicht in:BMC Pulm Med
Hauptverfasser: Hartmann, Erik K, Ziebart, Alexander, Thomas, Rainer, Liu, Tanghua, Schad, Arno, Tews, Martha, Moosmann, Bernd, Kamuf, Jens, Duenges, Bastian, Thal, Serge C, David, Matthias
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346123/
https://ncbi.nlm.nih.gov/pubmed/25879802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-015-0002-6
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