Transcriptome Analysis of Kidney Grafts Subjected to Normothermic Ex Vivo Perfusion Demonstrates an Enrichment of Mitochondrial Metabolism Genes

Normothermic ex vivo kidney perfusion (NEVKP) has demonstrated superior outcomes for donation-after-cardiovascular death grafts compared with static cold storage (SCS). To determine the mechanisms responsible for this, we performed an unbiased genome-wide microarray analysis. METHODS. Kidneys from 3...

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Bibliographic Details
Published in:Transplant Direct
Main Authors: Urbanellis, Peter, McEvoy, Caitriona M., Škrtić, Marko, Kaths, J. Moritz, Kollmann, Dagmar, Linares, Ivan, Ganesh, Sujani, Oquendo, Fabiola, Sharma, Manraj, Mazilescu, Laura, Goto, Toru, Noguchi, Yuki, John, Rohan, Mucsi, Istvan, Ghanekar, Anand, Bagli, Darius, Konvalinka, Ana, Selzner, Markus, Robinson, Lisa A.
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2021
Subjects:
Basic Science
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270593/
https://ncbi.nlm.nih.gov/pubmed/34258386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000001157
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