Transcriptome Analysis of Kidney Grafts Subjected to Normothermic Ex Vivo Perfusion Demonstrates an Enrichment of Mitochondrial Metabolism Genes

Normothermic ex vivo kidney perfusion (NEVKP) has demonstrated superior outcomes for donation-after-cardiovascular death grafts compared with static cold storage (SCS). To determine the mechanisms responsible for this, we performed an unbiased genome-wide microarray analysis. METHODS. Kidneys from 3...

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Publicat a:Transplant Direct
Autors principals: Urbanellis, Peter, McEvoy, Caitriona M., Škrtić, Marko, Kaths, J. Moritz, Kollmann, Dagmar, Linares, Ivan, Ganesh, Sujani, Oquendo, Fabiola, Sharma, Manraj, Mazilescu, Laura, Goto, Toru, Noguchi, Yuki, John, Rohan, Mucsi, Istvan, Ghanekar, Anand, Bagli, Darius, Konvalinka, Ana, Selzner, Markus, Robinson, Lisa A.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2021
Matèries:
Basic Science
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270593/
https://ncbi.nlm.nih.gov/pubmed/34258386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000001157
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