Pleiotropy method reveals genetic overlap between orofacial clefts at multiple novel loci from GWAS of multi-ethnic trios

Based on epidemiologic and embryologic patterns, nonsyndromic orofacial clefts– the most common craniofacial birth defects in humans– are commonly categorized into cleft lip with or without cleft palate (CL/P) and cleft palate alone (CP), which are traditionally considered to be etiologically distin...

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Dades bibliogràfiques
Publicat a:PLoS Genet
Autors principals: Ray, Debashree, Venkataraghavan, Sowmya, Zhang, Wanying, Leslie, Elizabeth J., Hetmanski, Jacqueline B., Weinberg, Seth M., Murray, Jeffrey C., Marazita, Mary L., Ruczinski, Ingo, Taub, Margaret A., Beaty, Terri H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270211/
https://ncbi.nlm.nih.gov/pubmed/34242216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009584
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