Pleiotropy method reveals genetic overlap between orofacial clefts at multiple novel loci from GWAS of multi-ethnic trios

Based on epidemiologic and embryologic patterns, nonsyndromic orofacial clefts– the most common craniofacial birth defects in humans– are commonly categorized into cleft lip with or without cleft palate (CL/P) and cleft palate alone (CP), which are traditionally considered to be etiologically distin...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Ray, Debashree, Venkataraghavan, Sowmya, Zhang, Wanying, Leslie, Elizabeth J., Hetmanski, Jacqueline B., Weinberg, Seth M., Murray, Jeffrey C., Marazita, Mary L., Ruczinski, Ingo, Taub, Margaret A., Beaty, Terri H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270211/
https://ncbi.nlm.nih.gov/pubmed/34242216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009584
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