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DNA G-Quadruplexes Contribute to CTCF Recruitment

G-quadruplex (G4) sites in the human genome frequently colocalize with CCCTC-binding factor (CTCF)-bound sites in CpG islands (CGIs). We aimed to clarify the role of G4s in CTCF positioning. Molecular modeling data suggested direct interactions, so we performed in vitro binding assays with quadruple...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Tikhonova, Polina, Pavlova, Iulia, Isaakova, Ekaterina, Tsvetkov, Vladimir, Bogomazova, Alexandra, Vedekhina, Tatjana, Luzhin, Artem V., Sultanov, Rinat, Severov, Vjacheslav, Klimina, Ksenia, Kantidze, Omar L., Pozmogova, Galina, Lagarkova, Maria, Varizhuk, Anna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8269367/
https://ncbi.nlm.nih.gov/pubmed/34209337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22137090
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