DNA G-Quadruplexes Contribute to CTCF Recruitment

G-quadruplex (G4) sites in the human genome frequently colocalize with CCCTC-binding factor (CTCF)-bound sites in CpG islands (CGIs). We aimed to clarify the role of G4s in CTCF positioning. Molecular modeling data suggested direct interactions, so we performed in vitro binding assays with quadruple...

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Publicado en:Int J Mol Sci
Main Authors: Tikhonova, Polina, Pavlova, Iulia, Isaakova, Ekaterina, Tsvetkov, Vladimir, Bogomazova, Alexandra, Vedekhina, Tatjana, Luzhin, Artem V., Sultanov, Rinat, Severov, Vjacheslav, Klimina, Ksenia, Kantidze, Omar L., Pozmogova, Galina, Lagarkova, Maria, Varizhuk, Anna
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8269367/
https://ncbi.nlm.nih.gov/pubmed/34209337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22137090
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