Cancer-Associated Fibroblasts Modulate Transcriptional Signatures Involved in Proliferation, Differentiation and Metastasis in Head and Neck Squamous Cell Carcinoma

SIMPLE SUMMARY: Cancer-associated fibroblasts (CAFs) are the major cellular component of the tumor microenvironment and have been shown to stimulate tumor growth, epithelial-to-mesenchymal transition (EMT), invasion, and radio-resistance. Radio-resistance leading to disease relapse is one of the maj...

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Publicado en:Cancers (Basel)
Autores principales: Wiechec, Emilia, Magan, Mustafa, Matic, Natasa, Ansell-Schultz, Anna, Kankainen, Matti, Monni, Outi, Johansson, Ann-Charlotte, Roberg, Karin
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8269044/
https://ncbi.nlm.nih.gov/pubmed/34283070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13133361
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