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A CD44(high)/EGFR(low) Subpopulation within Head and Neck Cancer Cell Lines Shows an Epithelial-Mesenchymal Transition Phenotype and Resistance to Treatment

Mortality in head and neck squamous cell carcinoma (HNSCC) is high due to emergence of therapy resistance which results in local and regional recurrences that may have their origin in resistant cancer stem cells (CSCs) or cells with an epithelial-mesenchymal transition (EMT) phenotype. In the presen...

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Autors principals: La Fleur, Linnea, Johansson, Ann-Charlotte, Roberg, Karin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458050/
https://ncbi.nlm.nih.gov/pubmed/23049743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044071
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