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A CD44(high)/EGFR(low) Subpopulation within Head and Neck Cancer Cell Lines Shows an Epithelial-Mesenchymal Transition Phenotype and Resistance to Treatment

Mortality in head and neck squamous cell carcinoma (HNSCC) is high due to emergence of therapy resistance which results in local and regional recurrences that may have their origin in resistant cancer stem cells (CSCs) or cells with an epithelial-mesenchymal transition (EMT) phenotype. In the presen...

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Detalhes bibliográficos
Main Authors: La Fleur, Linnea, Johansson, Ann-Charlotte, Roberg, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458050/
https://ncbi.nlm.nih.gov/pubmed/23049743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044071
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